
Product description:Nolvadex (tamoxifen) is a non-steroidal, triphenylethylene-based drug which displays a complex spectrum...
| Package | Price | Your save | Add to cart |
| 30 tabs x 20mg | $50.40 | $0.00 | ![]() |
| 60 tabs x 20mg | $84.00 | $16.80 | ![]() |
| 150 tabs x 20mg | $224.00 | $28.00 | ![]() |
Nolvadex (tamoxifen) is a non-steroidal, triphenylethylene-based drug which displays a complex spectrum of oestrogen antagonist and oestrogen agonist-like pharmacological effects in different tissues. In breast cancer patients, at the tumour level, tamoxifen acts primarily as an antioestrogen, preventing oestrogen binding to the oestrogen receptor. However, clinical studies have shown some benefit in oestrogen receptor negative tumours which may indicate other mechanisms of action. In the clinical situation, it is recognised that tamoxifen leads to reductions in levels of blood total cholesterol and low density lipoproteins in postmenopausal women of the order of 10–20%. Tamoxifen does not adversely affect bone mineral density.